{"id":29917,"date":"2026-08-09T13:45:00","date_gmt":"2026-08-09T18:45:00","guid":{"rendered":"https:\/\/okdiario.com\/metabolic\/en\/?p=29917"},"modified":"2026-08-08T23:04:17","modified_gmt":"2026-08-09T04:04:17","slug":"franco-berrino-warns-about-the-deadly-quartet-of-metabolic-syndrome-if-you-carry-belly-fat-your-risk-of-diabetes-and-infarction-climbs","status":"publish","type":"post","link":"https:\/\/okdiario.com\/metabolic\/en\/health\/franco-berrino-warns-about-the-deadly-quartet-of-metabolic-syndrome-if-you-carry-belly-fat-your-risk-of-diabetes-and-infarction-climbs-29917\/","title":{"rendered":"Franco Berrino warns about the deadly quartet of metabolic syndrome: if you carry belly fat, your risk of diabetes and infarction climbs"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Metabolic syndrome can build quietly while a person feels mostly fine. A larger waist, rising blood sugar, abnormal blood fats, and high blood pressure can arrive together, increasing the risk of heart disease, stroke, and type 2 diabetes.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Italian epidemiologist Franco Berrino says the body may begin responding surprisingly fast when a sedentary routine and heavily processed food give way to daily movement and a genuine <a href=\"https:\/\/okdiario.com\/metabolic\/en\/health\/eat-a-little-less-walk-briskly-and-add-one-pantry-staple-a-six-year-spanish-study-says-this-trio-could-help-hold-off-diabetes-29433\/\">Mediterranean diet<\/a>. His message is hopeful, but it is not a promise of an overnight cure.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What metabolic syndrome means<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Metabolic syndrome is not one disease. It is diagnosed when a person has at least three of five problems, including high blood glucose, high triglycerides, low HDL cholesterol, <a href=\"https:\/\/okdiario.com\/metabolic\/en\/psychology\/nearly-one-in-three-adults-has-high-blood-pressure-but-these-seven-daily-habits-can-lower-yours-naturally-though-one-matters-most-29094\/\">high blood pressure<\/a>, and excess fat around the waist. Roughly one in three U.S. adults is affected.<\/p>\n\n\n\n<div class=\"gb-element-a00da4e5\">\n<div><div class=\"gb-looper-46613eed\">\n<div class=\"gb-loop-item gb-loop-item-a8390598 post-29821 post type-post status-publish format-standard has-post-thumbnail hentry category-health resize-featured-image\">\n<h3 class=\"gb-text gb-text-24a51617\">Read More: <a href=\"https:\/\/okdiario.com\/metabolic\/en\/health\/when-your-blood-sugar-spikes-out-of-nowhere-these-five-simple-habits-could-help-you-take-back-control-of-your-diabetes-29821\/\">When your blood sugar spikes out of nowhere, these five simple habits could help you take back control of your diabetes<\/a><\/h3>\n<\/div>\n<\/div><\/div>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">The common thread is often insulin resistance, which means <a href=\"https:\/\/www.niddk.nih.gov\/health-information\/diabetes\/overview\/what-is-diabetes\/prediabetes-insulin-resistance\" target=\"_blank\" rel=\"noopener\">cells do not respond<\/a> properly to insulin and the body struggles to move sugar out of the blood. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Metabolic syndrome is also commonly associated with low-grade inflammation and impaired blood vessel function, helping explain why the cluster matters beyond any single test result.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Why improvement can come quickly<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u201cAfter only a few weeks of the diet, we saw reductions in blood sugar, triglycerides, cholesterol, waist circumference, and blood pressure,\u201d he wrote. He added that rigorous clinical trials have shown the syndrome can regress within months.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Regression has a specific meaning here. It means a person improves enough to no longer meet the diagnostic threshold for metabolic syndrome, not that the underlying tendency has disappeared forever. Old habits, weight gain, illness, or aging can push those numbers back in the wrong direction.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1800\" height=\"1013\" src=\"https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/08\/franco-berrino-metabolic-syndrome-belly-fat-risks.jpg\" alt=\"A medical checkup measuring waist circumference and assessing metabolic health risks like belly fat and diabetes.\" class=\"wp-image-29919\" srcset=\"https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/08\/franco-berrino-metabolic-syndrome-belly-fat-risks.jpg 1800w, https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/08\/franco-berrino-metabolic-syndrome-belly-fat-risks-300x169.jpg 300w, https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/08\/franco-berrino-metabolic-syndrome-belly-fat-risks-768x432.jpg 768w, https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/08\/franco-berrino-metabolic-syndrome-belly-fat-risks-1536x864.jpg 1536w, https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/08\/franco-berrino-metabolic-syndrome-belly-fat-risks-150x84.jpg 150w\" sizes=\"auto, (max-width: 1800px) 100vw, 1800px\" \/><figcaption class=\"wp-element-caption\">Epidemiologist Franco Berrino highlights how diet and lifestyle changes can reverse metabolic syndrome and reduce diabetes risks.<\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\">Still, early movement in laboratory results is plausible. Replacing sugary drinks, excess alcohol, salty packaged foods, trans fats, and large amounts of saturated fat with <a href=\"https:\/\/okdiario.com\/metabolic\/en\/health\/science-says-your-plate-may-quietly-fuel-inflammation-in-your-body-and-the-anti-inflammatory-eating-pattern-that-calms-it-is-simpler-than-you-think-28941\/\">fiber-rich plant foods<\/a> changes several risk factors at once. That is why blood tests may move before a person sees dramatic weight loss.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">A major trial supports the pattern<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">One influential randomized trial led by Katherine Esposito followed 180 sedentary adults with metabolic syndrome in Italy. Half received detailed advice to eat more whole grains, vegetables, fruit, nuts, and olive oil, while the others followed a more general lower-fat diet.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">After two years, only 40 people in the Mediterranean diet group still met the syndrome\u2019s criteria, compared with 78 in the control group. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The Mediterranean group also lost about 9 pounds on average, versus roughly 3 pounds in the comparison group, while showing better insulin sensitivity and lower inflammatory markers.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">That does not mean olive oil alone produced the result. Participants changed an entire eating pattern and received structured guidance. <\/p>\n\n\n\n<div class=\"gb-element-84d5c341\">\n<div><div class=\"gb-looper-03c6fe81\">\n<div class=\"gb-loop-item gb-loop-item-2178c136 post-29759 post type-post status-publish format-standard has-post-thumbnail hentry category-health resize-featured-image\">\n<h3 class=\"gb-text gb-text-46dc1e3b\">Read More: <a href=\"https:\/\/okdiario.com\/metabolic\/en\/health\/this-could-be-the-easiest-way-to-keep-type-2-diabetes-away-and-the-simple-daily-steps-you-need-take-barely-any-effort-29759\/\">This could be the easiest way to keep type 2 diabetes away, and the simple daily steps you need take barely any effort<\/a><\/h3>\n<\/div>\n<\/div><\/div>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">In practical terms, the benefit came from what filled the plate day after day, not from adding one fashionable ingredient to an otherwise unchanged diet.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What a real Mediterranean diet looks like<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The traditional pattern centers on vegetables, beans, lentils, whole grains, fruit, nuts, and <a href=\"https:\/\/okdiario.com\/metabolic\/en\/nutrition\/ask-a-room-of-cardiologists-what-they-eat-to-guard-their-own-hearts-and-almost-all-name-the-same-everyday-oil-29438\/\">extra-virgin olive oil<\/a>. Fish and cheese appear in moderate amounts, while red and processed meats, sweets, sugary drinks, and ultra-processed foods become occasional choices rather than everyday staples.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Extra-virgin olive oil contains polyphenols, plant compounds studied for their effects on inflammation and oxidation, but the diet works as a team. A drizzle of oil cannot cancel out a day built around soda, packaged snacks, and processed meat.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Movement matters too. U.S. guidance recommends at least 150 minutes of moderate activity each week, along with muscle-strengthening exercise on two days. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A brisk walk after dinner, taking the stairs, or breaking up long hours at a desk may sound ordinary, but ordinary habits are often the ones people can keep.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1800\" height=\"1013\" src=\"https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/08\/franco-berrino-metabolic-syndrome-belly-fat-diet.jpg\" alt=\"A healthy Mediterranean diet featuring fresh vegetables, olive oil, and whole grains, representing lifestyle habits to combat metabolic syndrome and belly fat.\" class=\"wp-image-29920\" srcset=\"https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/08\/franco-berrino-metabolic-syndrome-belly-fat-diet.jpg 1800w, https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/08\/franco-berrino-metabolic-syndrome-belly-fat-diet-300x169.jpg 300w, https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/08\/franco-berrino-metabolic-syndrome-belly-fat-diet-768x432.jpg 768w, https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/08\/franco-berrino-metabolic-syndrome-belly-fat-diet-1536x864.jpg 1536w, https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/08\/franco-berrino-metabolic-syndrome-belly-fat-diet-150x84.jpg 150w\" sizes=\"auto, (max-width: 1800px) 100vw, 1800px\" \/><figcaption class=\"wp-element-caption\">Epidemiologist Franco Berrino explains how addressing belly fat and adopting a Mediterranean lifestyle can rapidly reduce metabolic syndrome risk factors.<\/figcaption><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Why cancer researchers are paying attention<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The commentary also points to work at the Milan National Cancer Institute linking metabolic syndrome with breast cancer prognosis and recurrence.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Researchers have examined how abdominal obesity, <a href=\"https:\/\/okdiario.com\/metabolic\/en\/nutrition\/scientists-studied-49-pairs-of-identical-twins-and-found-a-single-immune-switch-that-may-decide-whether-your-body-stores-fat-29218\/\">insulin resistance<\/a>, and related metabolic changes may be associated with outcomes after a breast cancer diagnosis.<\/p>\n\n\n\n<div class=\"gb-element-d84f6281\">\n<div><div class=\"gb-looper-eb0ed5c5\">\n<div class=\"gb-loop-item gb-loop-item-1b58fe60 post-29659 post type-post status-publish format-standard has-post-thumbnail hentry category-health resize-featured-image\">\n<h3 class=\"gb-text gb-text-dc5c2674\">Read More: <a href=\"https:\/\/okdiario.com\/metabolic\/en\/health\/new-findings-suggest-diabetes-and-dementia-are-linked-more-closely-than-you-think-and-it-could-change-how-you-protect-your-brain-29659\/\">New findings suggest diabetes and dementia are linked more closely than you think, and it could change how you protect your brain<\/a><\/h3>\n<\/div>\n<\/div><\/div>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Those findings do not prove that changing diet alone prevents a tumor or stops a recurrence. They do show why oncology researchers care about blood sugar, waist size, blood pressure, and blood fats rather than treating them as unrelated numbers on a laboratory report.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Lifestyle first, but not medicine-free<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">For many people, food, activity, and weight management are central parts of treatment. However, the <a href=\"https:\/\/www.heart.org\/en\/health-topics\/metabolic-syndrome\/prevention-and-treatment-of-metabolic-syndrome\" target=\"_blank\" rel=\"noopener\">American Heart Association<\/a> notes that medications may still be needed when lifestyle changes do not adequately control blood pressure, cholesterol, or other conditions related to metabolic syndrome.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">That is the important balance. A Mediterranean lifestyle can be powerful and may produce measurable changes sooner than expected, but no one should stop prescribed medication without medical guidance. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A clinician can track the five risk factors and determine whether improvement is real, sustained, and safe.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The original commentary was published in <em>Corriere della Sera<\/em>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Metabolic syndrome can build quietly while a person feels mostly fine. A larger waist, rising blood sugar, abnormal blood fats, &#8230; <\/p>\n<p class=\"read-more-container\"><a title=\"Franco Berrino warns about the deadly quartet of metabolic syndrome: if you carry belly fat, your risk of diabetes and infarction climbs\" class=\"read-more button\" href=\"https:\/\/okdiario.com\/metabolic\/en\/health\/franco-berrino-warns-about-the-deadly-quartet-of-metabolic-syndrome-if-you-carry-belly-fat-your-risk-of-diabetes-and-infarction-climbs-29917\/#more-29917\" aria-label=\"Read more about Franco Berrino warns about the deadly quartet of metabolic syndrome: if you carry belly fat, your risk of diabetes and infarction climbs\">Read more<\/a><\/p>\n","protected":false},"author":18,"featured_media":29918,"comment_status":"open","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":["post-29917","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health","resize-featured-image"],"_links":{"self":[{"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/posts\/29917","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/users\/18"}],"replies":[{"embeddable":true,"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/comments?post=29917"}],"version-history":[{"count":1,"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/posts\/29917\/revisions"}],"predecessor-version":[{"id":29921,"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/posts\/29917\/revisions\/29921"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/media\/29918"}],"wp:attachment":[{"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/media?parent=29917"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/categories?post=29917"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/tags?post=29917"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}