{"id":29312,"date":"2026-07-23T06:00:00","date_gmt":"2026-07-23T11:00:00","guid":{"rendered":"https:\/\/okdiario.com\/metabolic\/en\/?p=29312"},"modified":"2026-07-22T09:25:26","modified_gmt":"2026-07-22T14:25:26","slug":"casey-harrell-lost-his-voice-to-als-then-a-brain-implant-handed-part-of-it-back-and-the-moment-stunned-his-doctors","status":"publish","type":"post","link":"https:\/\/okdiario.com\/metabolic\/en\/psychology\/casey-harrell-lost-his-voice-to-als-then-a-brain-implant-handed-part-of-it-back-and-the-moment-stunned-his-doctors-29312\/","title":{"rendered":"Casey Harrell lost his voice to ALS, then a brain implant handed part of it back, and the moment stunned his doctors"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">For Casey Harrell, holding a conversation had become a slow, demanding process. ALS had severely weakened his movement and speech, leaving him reliant on an interpreter or letter-by-letter typing with a head-controlled mouse.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A new implanted brain-computer interface now turns his attempted speech into text and lets him control a computer cursor at home.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Over 19 months, he used the system for more than 3,800 hours and communicated 183,060 sentences containing nearly 2 million words. His average speed reached 56 words per minute, and he rated 92% of everyday sentences as at least mostly correct. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The bigger breakthrough is independence, since it worked almost daily without researchers on site.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What ALS takes away<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Amyotrophic lateral sclerosis is a progressive disease that damages motor neurons, the <a href=\"https:\/\/okdiario.com\/metabolic\/en\/health\/scientists-may-have-found-a-way-to-repair-nerve-damage-in-multiple-sclerosis-with-the-approach-targeting-regeneration-instead-of-only-slowing-attacks-27992\/\">nerve cells<\/a> controlling voluntary muscles. As it advances, walking, talking, chewing, and breathing can become difficult as the brain loses control of those movements. <\/p>\n\n\n\n<div class=\"gb-element-a00da4e5\">\n<div><div class=\"gb-looper-46613eed\">\n<div class=\"gb-loop-item gb-loop-item-a8390598 post-29254 post type-post status-publish format-standard has-post-thumbnail hentry category-health resize-featured-image\">\n<h3 class=\"gb-text gb-text-24a51617\">Read More: <a href=\"https:\/\/okdiario.com\/metabolic\/en\/health\/your-gut-may-be-acting-like-a-second-brain-and-neurosurgeons-say-it-can-quietly-influence-your-mood-through-what-you-eat-29254\/\">Your gut may be acting like a second brain, and neurosurgeons say it can quietly influence your mood through what you eat\u00a0<\/a><\/h3>\n<\/div>\n<\/div><\/div>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">A person may still know exactly what they want to say, but the muscles needed to say it no longer cooperate.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Before the implant, Harrell communicated at roughly 6 to 7 words per minute with his existing methods. The new system was more than eight times faster on average. In everyday life, that can mean answering a question before the conversation has already moved on.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How the brain implant works<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The work was led by Nicholas Card, Sergey Stavisky, and David Brandman at the University of California, Davis. Collaborators came from the University Medical Center Utrecht Brain Center at Utrecht University, Brown University, and Massachusetts General Hospital.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In 2023, surgeons placed four microelectrode arrays, small grids with a total of 256 electrodes, in Harrell\u2019s left speech motor cortex. A <a href=\"https:\/\/www.braingate.org\/about-braingate\/\" target=\"_blank\" rel=\"noopener\">brain-computer interface<\/a> acts like a bridge between brain activity and a machine. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">When he tries to speak, software detects signal patterns and converts them into likely sounds and words on a screen.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1800\" height=\"1013\" src=\"https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/07\/casey-harrell-als-brain-computer-interface-uc-davis-1.jpg\" alt=\"A medical graphic illustrating a brain-computer interface implant translating neural activity into typed speech on a computer screen.\" class=\"wp-image-29316\" title=\"\" srcset=\"https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/07\/casey-harrell-als-brain-computer-interface-uc-davis-1.jpg 1800w, https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/07\/casey-harrell-als-brain-computer-interface-uc-davis-1-300x169.jpg 300w, https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/07\/casey-harrell-als-brain-computer-interface-uc-davis-1-768x432.jpg 768w, https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/07\/casey-harrell-als-brain-computer-interface-uc-davis-1-1536x864.jpg 1536w, https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/07\/casey-harrell-als-brain-computer-interface-uc-davis-1-150x84.jpg 150w\" sizes=\"auto, (max-width: 1800px) 100vw, 1800px\" \/><figcaption class=\"wp-element-caption\">Utilizing an advanced implanted brain-computer interface, ALS patient Casey Harrell successfully communicated nearly 2 million words from home over 19 months.<\/figcaption><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Speech and computer control together<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The implant does more than generate text. Harrell can imagine moving or squeezing his right hand to guide a cursor and click, while eye tracking helps him switch tools and select controls. The text can also be read aloud by a <a href=\"https:\/\/okdiario.com\/metabolic\/en\/psychology\/stephen-hawking-scientist-quiet-and-reserved-people-are-the-ones-with-the-strongest-and-most-active-minds-27055\/\">synthetic voice<\/a> designed to resemble the voice he had before ALS.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">That combination gave him access to email, text messages, web browsing, video calls, and work. He continued full-time employment despite <a href=\"https:\/\/okdiario.com\/metabolic\/en\/health\/two-patients-with-severe-autoimmune-disease-have-stayed-relapse-free-for-over-15-years-after-one-stem-cell-transplant-and-heres-what-they-got-28628\/\">severe paralysis<\/a>. Through the system, he described having \u201ca life that is more full of dynamic action\u201d with family, friends, and colleagues.<\/p>\n\n\n\n<figure class=\"wp-block-embed is-type-video is-provider-youtube wp-block-embed-youtube wp-embed-aspect-16-9 wp-has-aspect-ratio\"><div class=\"wp-block-embed__wrapper\">\n<iframe loading=\"lazy\" title=\"New Brain-Computer Interface (BCI) Allows Man with ALS to &amp;apos;Speak\u2019 Again Using Brain Implant and AI\" width=\"1200\" height=\"675\" src=\"https:\/\/www.youtube.com\/embed\/thPhBDVSxz0?feature=oembed\" frameborder=\"0\" allow=\"accelerometer; autoplay; clipboard-write; encrypted-media; gyroscope; picture-in-picture; web-share\" referrerpolicy=\"strict-origin-when-cross-origin\" allowfullscreen><\/iframe>\n<\/div><figcaption class=\"wp-element-caption\">YouTube: <em>@UCDavisHealth<\/em>.<\/figcaption><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">From a lab demo to a daily tool<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">A 2024 study from the same project decoded attempted speech with about 97% accuracy, but researchers still had to operate the equipment. Could someone rely on it day after day? The new work shows that one participant could.<\/p>\n\n\n\n<div class=\"gb-element-c4d2a660\">\n<div><div class=\"gb-looper-335d7b7a\">\n<div class=\"gb-loop-item gb-loop-item-3f93156b post-29165 post type-post status-publish format-standard has-post-thumbnail hentry category-health resize-featured-image\">\n<h3 class=\"gb-text gb-text-d00257df\">Read More: <a href=\"https:\/\/okdiario.com\/metabolic\/en\/health\/scientists-found-how-one-toxic-protein-hijacks-your-healthy-brain-cells-and-spreads-alzheimers-from-neuron-to-neuron-but-there-may-be-a-treatment-coming-29165\/\">Scientists found how one toxic protein hijacks your healthy brain cells and spreads Alzheimer&#8217;s from neuron to neuron, but there may be a treatment coming<\/a><\/h3>\n<\/div>\n<\/div><\/div>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">The updated system starts automatically, recalibrates much of its speech software in the background, and uses a simplified menu. Trained caregivers still connect the external hardware, a process taking about 20 minutes, but Harrell could then use it for up to 19 hours without further help. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">No researcher had to remain in the room.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Accuracy needs context<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">In structured tests, the system reached 99.2% word accuracy with a vocabulary of 125,000 words. Everyday conversation was messier. At home, 53.3% of sentences were exactly correct, 12.9% were corrected, and 26.1% were rated mostly correct.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Can the implant read every thought? No, it decodes activity linked to deliberate attempts to speak, move a cursor, or click, and Harrell can correct the output. A privacy setting also lets him stop the system from recording data when he chooses.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1800\" height=\"1013\" src=\"https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/07\/casey-harrell-als-brain-computer-interface-study.jpg\" alt=\"A medical visualization of a brain computer interface system, representing the technology used by Casey Harrell to convert attempted speech into text and control a computer after being diagnosed with ALS.\" class=\"wp-image-29317\" title=\"\" srcset=\"https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/07\/casey-harrell-als-brain-computer-interface-study.jpg 1800w, https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/07\/casey-harrell-als-brain-computer-interface-study-300x169.jpg 300w, https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/07\/casey-harrell-als-brain-computer-interface-study-768x432.jpg 768w, https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/07\/casey-harrell-als-brain-computer-interface-study-1536x864.jpg 1536w, https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/07\/casey-harrell-als-brain-computer-interface-study-150x84.jpg 150w\" sizes=\"auto, (max-width: 1800px) 100vw, 1800px\" \/><figcaption class=\"wp-element-caption\">A groundbreaking clinical study published in Nature Medicine demonstrates that an implanted brain computer interface allowed an ALS patient to communicate independently at home for over 19 months, achieving an average speaking speed of 56 words per minute.<\/figcaption><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Why the home setting matters<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Research devices can impress during a short laboratory session and still struggle in daily life. Here, the interface remained useful through changing routines, fatigue, long sentences, and months of neural signal variation. That endurance is central to the result.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">In practical terms, the implant gave Harrell more control over when and how he communicated. <\/p>\n\n\n\n<div class=\"gb-element-f6fdd40c\">\n<div><div class=\"gb-looper-312aa4ad\">\n<div class=\"gb-loop-item gb-loop-item-9a799459 post-28957 post type-post status-publish format-standard has-post-thumbnail hentry category-health resize-featured-image\">\n<h3 class=\"gb-text gb-text-8dcade87\">Read More: <a href=\"https:\/\/okdiario.com\/metabolic\/en\/health\/if-youre-over-50-and-quietly-worried-about-your-memory-scientists-built-a-free-online-test-that-checks-your-brain-in-minutes-28957\/\">If you&#8217;re over 50 and quietly worried about your memory, scientists built a free, online test that checks your brain in minutes<\/a><\/h3>\n<\/div>\n<\/div><\/div>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">A work email, a private message, or a dinner-table conversation may sound routine, but those moments are the real test of <a href=\"https:\/\/okdiario.com\/metabolic\/en\/health\/deaf-and-hard-of-hearing-nhs-users-have-complained-that-the-312-batteries-in-their-hearing-aids-ran-out-and-they-had-to-switch-them-off-to-save-power-even-though-the-nhs-itself-later-stated-that-the-27476\/\">assistive technology<\/a>. This study suggests a brain implant can begin to pass that test at home.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Limits and next steps<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The findings come from one participant, so it is unclear whether others will achieve similar results. The system also requires brain surgery, wired connections through the skin, daily caregiver setup, and a bulky computer cart.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">It remains an <a href=\"https:\/\/clinicaltrials.gov\/study\/NCT00912041\" target=\"_blank\" rel=\"noopener\">investigational device<\/a>, not a treatment available for routine clinical use.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Future versions will need to be smaller, easier to start, wireless or fully implanted, and tested in more people. Researchers also want natural home conversation to match the accuracy seen in controlled tests. Promising, yes, but ready for everyday medical use? Not yet.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The official study was published in <a href=\"https:\/\/www.nature.com\/articles\/s41591-026-04414-6\" target=\"_blank\" rel=\"noopener\"><em>Nature Medicine<\/em><\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>For Casey Harrell, holding a conversation had become a slow, demanding process. ALS had severely weakened his movement and speech, &#8230; <\/p>\n<p class=\"read-more-container\"><a title=\"Casey Harrell lost his voice to ALS, then a brain implant handed part of it back, and the moment stunned his doctors\" class=\"read-more button\" href=\"https:\/\/okdiario.com\/metabolic\/en\/psychology\/casey-harrell-lost-his-voice-to-als-then-a-brain-implant-handed-part-of-it-back-and-the-moment-stunned-his-doctors-29312\/#more-29312\" aria-label=\"Read more about Casey Harrell lost his voice to ALS, then a brain implant handed part of it back, and the moment stunned his doctors\">Read more<\/a><\/p>\n","protected":false},"author":20,"featured_media":29315,"comment_status":"open","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[19],"tags":[],"class_list":["post-29312","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-psychology","resize-featured-image"],"_links":{"self":[{"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/posts\/29312","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/comments?post=29312"}],"version-history":[{"count":1,"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/posts\/29312\/revisions"}],"predecessor-version":[{"id":29318,"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/posts\/29312\/revisions\/29318"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/media\/29315"}],"wp:attachment":[{"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/media?parent=29312"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/categories?post=29312"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/tags?post=29312"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}