{"id":29210,"date":"2026-07-20T07:45:00","date_gmt":"2026-07-20T12:45:00","guid":{"rendered":"https:\/\/okdiario.com\/metabolic\/en\/?p=29210"},"modified":"2026-07-19T16:46:06","modified_gmt":"2026-07-19T21:46:06","slug":"just-5-grams-of-this-black-seed-lowered-bad-cholesterol-in-eight-weeks-and-blocked-fat-from-building-up-yet-most-people-ignore-it","status":"publish","type":"post","link":"https:\/\/okdiario.com\/metabolic\/en\/health\/just-5-grams-of-this-black-seed-lowered-bad-cholesterol-in-eight-weeks-and-blocked-fat-from-building-up-yet-most-people-ignore-it-29210\/","title":{"rendered":"Just 5 grams of this black seed lowered bad cholesterol in eight weeks and blocked fat from building up, yet most people ignore it"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">A spice used in curries and flatbreads may have more to offer than flavor. In a randomized trial, adults who took about 0.18 ounces of black cumin seed powder each day for eight weeks had<a href=\"https:\/\/okdiario.com\/metabolic\/en\/health\/scientists-found-a-hidden-mechanism-in-your-liver-that-attacks-ldl-receptors-and-it-could-change-the-fight-against-high-cholesterol-for-you-28521\/\"> lower LDL cholesterol<\/a>, triglycerides, and total cholesterol, along with a small rise in HDL cholesterol. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Lab tests also found that an extract slowed fat buildup as immature fat cells developed.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">That sounds like a simple kitchen fix, but it\u2019s not yet. The human study included only 42 people, lasted two months, and did not use a placebo, so the findings are an early signal rather than proof that black cumin prevents obesity or replaces cholesterol treatment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the small trial found<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Researchers enrolled adults with body mass indexes in the overweight or obese range and borderline or high cholesterol who were not taking cholesterol medication. <\/p>\n\n\n\n<div class=\"gb-element-a00da4e5\">\n<div><div class=\"gb-looper-46613eed\">\n<div class=\"gb-loop-item gb-loop-item-a8390598 post-29196 post type-post status-publish format-standard has-post-thumbnail hentry category-nutrition resize-featured-image\">\n<h3 class=\"gb-text gb-text-24a51617\">Read More: <a href=\"https:\/\/okdiario.com\/metabolic\/en\/nutrition\/a-banana-for-nurses-eggs-for-couriers-tell-me-what-you-do-for-a-living-and-ill-tell-you-what-you-should-be-eating-29196\/\">A banana for nurses, eggs for couriers: tell me what you do for a living and I&#8217;ll tell you what you should be eating<\/a><\/h3>\n<\/div>\n<\/div><\/div>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Twenty-two people received the daily powder, described as roughly one tablespoon, while 20 received no supplement. Both groups received the same diet and lifestyle guidance.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Average total cholesterol fell from 217.6 to 202.0 mg\/dL, a drop of about 7%. LDL fell from 149.0 to 134.8, about 9.5%, and<a href=\"https:\/\/okdiario.com\/metabolic\/en\/nutrition\/a-dietitian-built-a-seven-day-high-fiber-meal-plan-to-lower-your-triglycerides-and-the-everyday-foods-on-it-might-surprise-you-28681\/\"> triglycerides<\/a> dropped from 175.8 to 159.3, about 9.4%. HDL rose from 33.5 to 35.3, about 5.4%, while the control group showed no significant change.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Why the cholesterol shift matters<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">LDL is often called <a href=\"https:\/\/www.heart.org\/en\/health-topics\/cholesterol\/hdl-good-ldl-bad-cholesterol-and-triglycerides\" target=\"_blank\" rel=\"noopener\">\u201cbad\u201d cholesterol<\/a> because too much can collect inside artery walls. HDL helps carry some cholesterol back to the liver, while triglycerides store extra energy from food. When LDL and triglycerides run high, especially alongside low HDL, heart attack and stroke risk can rise.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">One detail is easy to lose in the headline. The averages moved in a favorable direction, but they did not suddenly become ideal. After eight weeks, total cholesterol remained near 202, LDL near 135, triglycerides near 159, and HDL near 35, while healthy targets vary according to a <a href=\"https:\/\/okdiario.com\/metabolic\/en\/health\/this-is-why-you-should-pay-attention-your-cholesterol-numbers-and-what-they-actually-mean-even-when-your-labs-look-fine-28170\/\">person\u2019s overall risk<\/a>.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1800\" height=\"1013\" src=\"https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/07\/black-cumin-seeds-nigella-sativa-oil-cholesterol-study.jpg\" alt=\"Bowl of black cumin (Nigella sativa) seeds with bottles of black seed oil, a natural product studied for its potential effects on cholesterol and metabolic health.\" class=\"wp-image-29214\" title=\"\" srcset=\"https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/07\/black-cumin-seeds-nigella-sativa-oil-cholesterol-study.jpg 1800w, https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/07\/black-cumin-seeds-nigella-sativa-oil-cholesterol-study-300x169.jpg 300w, https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/07\/black-cumin-seeds-nigella-sativa-oil-cholesterol-study-768x432.jpg 768w, https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/07\/black-cumin-seeds-nigella-sativa-oil-cholesterol-study-1536x864.jpg 1536w, https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/07\/black-cumin-seeds-nigella-sativa-oil-cholesterol-study-150x84.jpg 150w\" sizes=\"auto, (max-width: 1800px) 100vw, 1800px\" \/><figcaption class=\"wp-element-caption\"><br>Black cumin seeds and black seed oil have attracted scientific interest after research linked daily consumption to improvements in cholesterol markers.<\/figcaption><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">What happened in fat cells<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The second part of the research took place in mouse cells commonly used to study<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK555602\/\" target=\"_blank\" rel=\"noopener\"> adipogenesis<\/a>, the process that turns immature cells into mature fat-storing cells. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">At the highest tested dose, black cumin extract reduced triglyceride buildup inside those cells by about 41%. The extract also reduced the activity of genes that help fat cells mature and build lipids.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">A petri dish is not a person. Cell experiments can reveal a possible mechanism, but they cannot show that eating the spice will cause weight loss or stop new<a href=\"https:\/\/okdiario.com\/metabolic\/en\/nutrition\/visceral-fat-isnt-just-belly-fat-it-builds-up-around-your-organs-and-nutritionists-point-to-four-everyday-factors-that-cause-it-to-skyrocket-without-you-even-realizing-it-one-of-t-27364\/\"> body fat<\/a> from forming. That distinction matters because the human trial reported blood fats and appetite, not a reduction in body weight.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Black cumin is not regular cumin<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Black cumin comes from<a href=\"https:\/\/powo.science.kew.org\/taxon\/urn%3Alsid%3Aipni.org%3Anames%3A711687-1\/general-information\" target=\"_blank\" rel=\"noopener\"> Nigella sativa<\/a> and is also called black seed. It is not the tan cumin commonly shaken into chili or taco seasoning, even though the names sound similar. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The small black seeds are used in South Asian and Middle Eastern cooking and contain plant compounds such as phenols, flavonoids, and thymoquinone.<\/p>\n\n\n\n<div class=\"gb-element-842c99f7\">\n<div><div class=\"gb-looper-f83b277e\">\n<div class=\"gb-loop-item gb-loop-item-820785a5 post-29192 post type-post status-publish format-standard has-post-thumbnail hentry category-health resize-featured-image\">\n<h3 class=\"gb-text gb-text-34272f32\">Read More: <a href=\"https:\/\/okdiario.com\/metabolic\/en\/health\/scientists-say-adults-under-50-are-aging-faster-than-past-generations-which-could-help-explain-why-cancer-cases-keep-climbing-among-the-young-29192\/\">Scientists say adults under 50 are aging faster than past generations, which could help explain why cancer cases keep climbing among the young<\/a><\/h3>\n<\/div>\n<\/div><\/div>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">The work was led by first author<a href=\"https:\/\/cvasu.ac.bd\/user-profile\/180\" target=\"_blank\" rel=\"noopener\"> Shamima Ahmed<\/a> and senior researcher Akiko Kojima-Yuasa, linking Osaka Metropolitan University in Japan with Chattogram Veterinary and <a href=\"https:\/\/cvasu.ac.bd\/\" target=\"_blank\" rel=\"noopener\">Animal Sciences University<\/a> in Bangladesh. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">It also fits a 2016 meta-analysis of <a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/26875640\/\" target=\"_blank\" rel=\"noopener\">17 randomized trials<\/a>, which found average reductions of 15.7 mg\/dL in total cholesterol, 14.1 in LDL, and 20.6 in triglycerides. That pooled analysis did not find an overall HDL increase, although seed powder performed better than oil for that measure.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the study cannot prove<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The biggest weakness is the lack of a placebo. The authors acknowledged that this could introduce bias, even though the blood tests were assessed by blinded investigators. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The trial was also small, short, and conducted at one location, making it hard to know whether the same results would appear in a larger and more diverse group.<\/p>\n\n\n\n<div class=\"gb-element-be755c38\">\n<div><div class=\"gb-looper-9d2ebe51\">\n<div class=\"gb-loop-item gb-loop-item-746d5270 post-29183 post type-post status-publish format-standard has-post-thumbnail hentry category-health resize-featured-image\">\n<h3 class=\"gb-text gb-text-cf75104a\">Read More: <a href=\"https:\/\/okdiario.com\/metabolic\/en\/health\/john-van-swieten-neurologist-on-hereditary-dementia-most-dont-want-to-know-precisely-because-theres-still-no-treatment-29183\/\">John van Swieten, neurologist on hereditary dementia: &#8216;Most don&#8217;t want to know, precisely because there&#8217;s still no treatment&#8217;<\/a><\/h3>\n<\/div>\n<\/div><\/div>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">The research did not measure heart attacks, long-term weight loss, or actual prevention of obesity-related disease. <\/p>\n\n\n\n<p class=\"wp-block-paragraph\">No significant adverse effects were reported during the eight weeks, but that does not establish long-term safety. People with high cholesterol should not replace<a href=\"https:\/\/okdiario.com\/metabolic\/en\/health\/statins-are-under-the-microscope-again-and-even-though-theyre-controversial-they-remain-foundational-for-preventing-cardiovascular-disease-28282\/\"> prescribed treatment<\/a> or medical advice with a spice based on one small trial.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Kojima-Yuasa said, \u201cWe hope to perform longer-term and larger-scale clinical trials to investigate the effects of black cumin on metabolism.\u201d That is the right next step, especially for<a href=\"https:\/\/okdiario.com\/metabolic\/en\/health\/prediabetes-can-move-silently-for-years-and-the-damage-may-begin-before-many-people-ever-see-a-clear-warning-sign-28402\/\"> insulin resistance<\/a>, inflammation, and whether the cholesterol changes last.\u00a0<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The full study was published in<a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/fsn3.70888\" target=\"_blank\" rel=\"noopener\"> <\/a><em><a href=\"https:\/\/onlinelibrary.wiley.com\/doi\/10.1002\/fsn3.70888\" target=\"_blank\" rel=\"noopener\">Food Science &amp; Nutrition<\/a>.<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A spice used in curries and flatbreads may have more to offer than flavor. In a randomized trial, adults who &#8230; <\/p>\n<p class=\"read-more-container\"><a title=\"Just 5 grams of this black seed lowered bad cholesterol in eight weeks and blocked fat from building up, yet most people ignore it\" class=\"read-more button\" href=\"https:\/\/okdiario.com\/metabolic\/en\/health\/just-5-grams-of-this-black-seed-lowered-bad-cholesterol-in-eight-weeks-and-blocked-fat-from-building-up-yet-most-people-ignore-it-29210\/#more-29210\" aria-label=\"Read more about Just 5 grams of this black seed lowered bad cholesterol in eight weeks and blocked fat from building up, yet most people ignore it\">Read more<\/a><\/p>\n","protected":false},"author":19,"featured_media":29213,"comment_status":"open","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":["post-29210","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health","resize-featured-image"],"_links":{"self":[{"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/posts\/29210","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/users\/19"}],"replies":[{"embeddable":true,"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/comments?post=29210"}],"version-history":[{"count":3,"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/posts\/29210\/revisions"}],"predecessor-version":[{"id":29215,"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/posts\/29210\/revisions\/29215"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/media\/29213"}],"wp:attachment":[{"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/media?parent=29210"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/categories?post=29210"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/tags?post=29210"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}