{"id":27841,"date":"2026-06-09T15:45:00","date_gmt":"2026-06-09T20:45:00","guid":{"rendered":"https:\/\/okdiario.com\/metabolic\/en\/?p=27841"},"modified":"2026-06-09T06:22:59","modified_gmt":"2026-06-09T11:22:59","slug":"a-first-genetic-analysis-of-the-cruise-hantavirus-case-confirmed-it-was-the-andes-variant-and-the-twist-is-what-it-did-not-show-no-mutations-that-change-the-story","status":"publish","type":"post","link":"https:\/\/okdiario.com\/metabolic\/en\/health\/a-first-genetic-analysis-of-the-cruise-hantavirus-case-confirmed-it-was-the-andes-variant-and-the-twist-is-what-it-did-not-show-no-mutations-that-change-the-story-27841\/","title":{"rendered":"A first genetic analysis of the cruise hantavirus case confirmed it was the Andes variant, and the twist is what it did not show, no mutations that change the story"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">The first complete genetic readout from a Swiss passenger tied to the MV Hondius outbreak has confirmed what health teams feared most. The virus belongs to the Andes hantavirus group, the rare South American form known for severe lung disease and limited person-to-person spread.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">But the same analysis also brings a calmer finding. Scientists did not see the genetic reshuffling that would suggest a brand-new virus, while European health officials reported 13 total cases and three deaths in the cruise-linked outbreak as of May 26, 2026.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the genome shows<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The virus was sequenced from blood samples taken from a Swiss resident who had traveled on the MV Hondius. Teams at the <a href=\"https:\/\/www.uzh.ch\/en.html\" target=\"_blank\" rel=\"noopener\">University of Zurich<\/a> and Geneva University Hospitals used Illumina technology, a tool that reads the virus\u2019s genetic code piece by piece.<\/p>\n\n\n\n<div class=\"gb-element-a00da4e5\">\n<div><div class=\"gb-looper-46613eed\">\n<div class=\"gb-loop-item gb-loop-item-a8390598 post-27841 post type-post status-publish format-standard has-post-thumbnail hentry category-health resize-featured-image\">\n<h3 class=\"gb-text gb-text-24a51617\">Read More: <a href=\"https:\/\/okdiario.com\/metabolic\/en\/health\/a-first-genetic-analysis-of-the-cruise-hantavirus-case-confirmed-it-was-the-andes-variant-and-the-twist-is-what-it-did-not-show-no-mutations-that-change-the-story-27841\/\">A first genetic analysis of the cruise hantavirus case confirmed it was the Andes variant, and the twist is what it did not show, no mutations that change the story<\/a><\/h3>\n<\/div>\n<\/div><\/div>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Sequencing is less like a regular test and more like reading the virus\u2019s instruction manual. Francisco Javier P\u00e9rez-Rodr\u00edguez, a Spanish scientist involved in the work, said the sequence also helps confirm that PCR tests aimed at Andes virus should be able to detect this outbreak strain.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Why Andes matters<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Hantaviruses usually spread from rodents to <a href=\"https:\/\/okdiario.com\/metabolic\/en\/health\/confirmed-the-fungus-that-spreads-through-scratches-from-infected-cats-and-can-be-transmitted-to-humans-27389\/\">people<\/a> through contaminated urine, droppings, or saliva. The Andes virus is different because it is the only hantavirus known to spread, rarely, from one infected person to another through close contact.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">That is why a cruise ship is such a difficult setting. Cabins, shared meals, narrow corridors, and days of repeated contact can give a rare virus more chances than it would get in ordinary life. It is not measles, and public health agencies are not describing a pandemic threat.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">No new viral reshuffling<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The key phrase here is \u201creassortment.\u201d In simple terms, it means two related viruses infect the same cell and swap large pieces of genetic material, creating something more like a new version.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The Swiss genome did not show that warning sign. Estanislao Nistal Vill\u00e1n, a virology researcher at CEU San Pablo University, described the sequence as close to known Andes virus samples, especially those linked to Argentina in 2018 and 2019.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">The chain is still being rebuilt<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">One genome cannot tell the whole story. More samples from other patients are needed to show whether the <a href=\"https:\/\/okdiario.com\/metabolic\/en\/health\/most-people-dont-realize-that-candida-auris-a-fungus-contracted-in-hospitals-may-not-be-best-fought-with-a-more-lethal-substance-but-rather-with-a-smarter-strategy-blocking-the-mechanism-24976\/\">infections<\/a> came mostly from recent person-to-person spread or from more than one exposure to infected rodents.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Early comparisons of available sequences suggest the cruise outbreak viruses are very similar, which supports the idea of a limited origin followed by transmission on board. <\/p>\n\n\n\n<div class=\"gb-element-c8610a1d\">\n<div><div class=\"gb-looper-027a5548\">\n<div class=\"gb-loop-item gb-loop-item-4517b23f post-27808 post type-post status-publish format-standard has-post-thumbnail hentry category-cosmetics resize-featured-image\">\n<h3 class=\"gb-text gb-text-2fb6e2a9\">Read More: <a href=\"https:\/\/okdiario.com\/metabolic\/en\/cosmetics\/an-anti-wrinkle-tea-is-being-credited-with-boosting-collagen-and-changing-skin-care-routines-and-the-twist-is-what-happens-when-you-treat-it-like-a-daily-signal-instead-of-a-miracle-27808\/\">An \u201canti-wrinkle tea\u201d is being credited with boosting collagen and changing skin care routines, and the twist is what happens when you treat it like a daily signal instead of a miracle drink<\/a><\/h3>\n<\/div>\n<\/div><\/div>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">Still, scientists have been careful to say the picture can change as more patient samples and environmental data arrive.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">A warning from Patagonia<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The current outbreak immediately brought attention back to a 2018-2019 Andes virus outbreak in Argentina. That earlier event showed how a rare virus can move through close social contact, especially when people gather indoors and do not yet know a dangerous infection is spreading.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">That lesson matters here. A cruise is not a birthday party or a family home, but it can create the same basic problem, people spending long stretches of time together in enclosed spaces. The trouble is, hantavirus can begin like the flu.<\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"1800\" height=\"1013\" src=\"https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/06\/hantavirus-andes-variant-genetic-analysis-hondius-1.jpg\" alt=\"A laboratory visualization of the Andes hantavirus genome sequence isolated from a passenger of the MV Hondius cruise ship.\" class=\"wp-image-27843\" title=\"\" srcset=\"https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/06\/hantavirus-andes-variant-genetic-analysis-hondius-1.jpg 1800w, https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/06\/hantavirus-andes-variant-genetic-analysis-hondius-1-300x169.jpg 300w, https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/06\/hantavirus-andes-variant-genetic-analysis-hondius-1-768x432.jpg 768w, https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/06\/hantavirus-andes-variant-genetic-analysis-hondius-1-1536x864.jpg 1536w, https:\/\/okdiario.com\/metabolic\/en\/wp-content\/uploads\/2026\/06\/hantavirus-andes-variant-genetic-analysis-hondius-1-150x84.jpg 150w\" sizes=\"auto, (max-width: 1800px) 100vw, 1800px\" \/><figcaption class=\"wp-element-caption\">Genomic sequencing confirms the Andes variant of the hantavirus is responsible for the cruise outbreak, with no signs of significant viral mutation.<\/figcaption><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">What passengers should watch for<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">Early symptoms can include fever, fatigue, muscle aches, headache, dizziness, chills, nausea, vomiting, diarrhea, or abdominal pain. Some people later develop <a href=\"https:\/\/okdiario.com\/metabolic\/en\/health\/the-reason-why-thousands-of-people-are-placing-a-metal-spoon-in-their-window-27273\/\">cough and shortness of breath<\/a>, which is when medical care becomes urgent.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">WHO has said the incubation period can last up to six weeks, so more cases after disembarkation are not unexpected. As of May 27, the agency said current evidence points to human-to-human transmission on the ship, while the risk to the global population remains low.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Why sequencing matters now<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">The genome is the outbreak\u2019s black box. It can help investigators understand where the virus may have come from, how long it had been moving, and whether the same strain appears in different patients.<\/p>\n\n\n\n<div class=\"gb-element-2d4e066d\">\n<div><div class=\"gb-looper-5674e861\">\n<div class=\"gb-loop-item gb-loop-item-15ab3031 post-27803 post type-post status-publish format-standard has-post-thumbnail hentry category-psychology resize-featured-image\">\n<h3 class=\"gb-text gb-text-c729d9cf\">Read More: <a href=\"https:\/\/okdiario.com\/metabolic\/en\/psychology\/carl-jung-psychologist-loneliness-does-not-come-from-having-no-people-around-but-from-being-unable-to-communicate-the-things-that-seem-important-to-oneself-27803\/\">Carl Jung, psychologist: \u201cLoneliness does not come from having no people around, but from being unable to communicate the things that seem important to oneself\u201d<\/a><\/h3>\n<\/div>\n<\/div><\/div>\n<\/div>\n\n\n\n<p class=\"wp-block-paragraph\">For now, the message is cautious but important. The virus is Andes, it is dangerous, and it deserves close monitoring, but the first complete genetic analysis does not point to a strange new mutant strain.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">The official sequence report has been published in <a href=\"https:\/\/virological.org\/t\/complete-sequence-of-orthohantavirus-andesense-virus-swiss-resident-2026\/1023\" target=\"_blank\" rel=\"noopener\"><em>Virological.org<\/em><\/a>.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>The first complete genetic readout from a Swiss passenger tied to the MV Hondius outbreak has confirmed what health teams &#8230; <\/p>\n<p class=\"read-more-container\"><a title=\"A first genetic analysis of the cruise hantavirus case confirmed it was the Andes variant, and the twist is what it did not show, no mutations that change the story\" class=\"read-more button\" href=\"https:\/\/okdiario.com\/metabolic\/en\/health\/a-first-genetic-analysis-of-the-cruise-hantavirus-case-confirmed-it-was-the-andes-variant-and-the-twist-is-what-it-did-not-show-no-mutations-that-change-the-story-27841\/#more-27841\" aria-label=\"Read more about A first genetic analysis of the cruise hantavirus case confirmed it was the Andes variant, and the twist is what it did not show, no mutations that change the story\">Read more<\/a><\/p>\n","protected":false},"author":19,"featured_media":27842,"comment_status":"open","ping_status":"","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[13],"tags":[],"class_list":["post-27841","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health","resize-featured-image"],"_links":{"self":[{"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/posts\/27841","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/users\/19"}],"replies":[{"embeddable":true,"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/comments?post=27841"}],"version-history":[{"count":2,"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/posts\/27841\/revisions"}],"predecessor-version":[{"id":27860,"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/posts\/27841\/revisions\/27860"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/media\/27842"}],"wp:attachment":[{"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/media?parent=27841"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/categories?post=27841"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/okdiario.com\/metabolic\/en\/wp-json\/wp\/v2\/tags?post=27841"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}